extremal hypoxia - vertaling naar russisch
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extremal hypoxia - vertaling naar russisch

FAMILY OF PROTEIN COMPLEXES
Hypoxia inducible factor; Hypoxia Inducible Factors; Hypoxia-inducible factor 1; Hypoxia inducible factor 1a; Hypoxia Inducible Factor; HIF-1; Hypoxia-inducible factors; Hypoxia inducible factors; Hypoxia signaling; Hypoxia-inducible factor-1; Hif1
  • Nobel Prize in Physiology or Medicine 2019: How Cells Sense and Adapt to Oxygen Availability. Under normoxic conditions, Hif-1 alpha is hydroxylated at two proline residues. It then associates with VHL and is tagged with ubiquitin resulting in proteasomal degradation. Under hypoxic conditions, Hif-1 alpha translocates to the cell nucleus and associates with Hif-1 beta. This complex then binds to the HRE region of the DNA resulting in the transcription of genes that are involved in a multitude of processes including erythropoesis, glycolysis, and angiogenesis.

extremal hypoxia      

медицина

экстремальная гипоксия

fetal hypoxia         
  • 210px
HUMAN DISEASE
Fetal hypoxia

медицина

гипоксия плода

oxygen starvation         
CONDITION IN WHICH THE BODY OR A REGION OF THE BODY IS DEPRIVED OF ADEQUATE OXYGEN SUPPLY AT THE TISSUE LEVEL
Anemic hypoxia; Oxygen starvation; Tissue hypoxia; Altitude hypoxia; Oxygen-shortage; Oxygen shortage; Hypoxiation; Oxygen deficiency; Hypoxic tissue; Hypoxic tissues; Localized hypoxia; Localised hypoxia
кислородное голодание

Definitie

hypoxia
[h??'p?ks??]
¦ noun Medicine deficiency in the amount of oxygen reaching the tissues.
?Ecology oxygen deficiency in a biotic environment.
Derivatives
hypoxic adjective
Origin
1940s: from hypo- + oxygen + -ia1.

Wikipedia

Hypoxia-inducible factor

Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreases in available oxygen in the cellular environment, or hypoxia. They are only present in parahoxozoan animals.

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